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Polyfunctional branched nitrogen-containing p-tert-butylthiacalix[4]arene derivatives as efficient agents for packaging calf thymus DNA

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dc.contributor.author Yakimova L.
dc.contributor.author Puplampu J.
dc.contributor.author Evtugin G.
dc.contributor.author Stoikov I.
dc.date.accessioned 2018-04-05T07:09:34Z
dc.date.available 2018-04-05T07:09:34Z
dc.date.issued 2017
dc.identifier.issn 1066-5285
dc.identifier.uri http://dspace.kpfu.ru/xmlui/handle/net/129838
dc.description.abstract © 2017, Springer Science+Business Media, LLC, part of Springer Nature. Polyfunctional p-tert-butylthiacalix[4]arenes tetrasubstituted at the lower rim with nitrogen-containing fragments in the cone, partial cone, and 1,3-alternate conformations were investigated in the processes of calf thymus DNA packaging. The influence of the macrocycle structure and composition on their ability to pack DNA into nano-sized particles was considered. UV spectroscopy and dynamic light scattering results showed that the synthesized p-tert-butylthiacalix[4] arenes functionalized at the lower rim with polyamine fragments in the cone and 1,3-alternate conformations can compact calf thymus DNA into nanosized particles ( < 100 nm). A new type of synthetic receptors based on the 1,3-alternate stereoisomer of p-tert-butylthiacalix[4]arene with ester, hydroxy, and tertiary amino groups was suggested for packaging DNA to nanoparticles of 51—85 nm in size.
dc.relation.ispartofseries Russian Chemical Bulletin
dc.subject calf thymus DNA
dc.subject DNA packaging
dc.subject dynamic light scattering
dc.subject p-tert-butylthiacalix[4]arene
dc.subject synthesis
dc.title Polyfunctional branched nitrogen-containing p-tert-butylthiacalix[4]arene derivatives as efficient agents for packaging calf thymus DNA
dc.type Article
dc.relation.ispartofseries-issue 8
dc.relation.ispartofseries-volume 66
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 1515
dc.source.id SCOPUS10665285-2017-66-8-SID85037640822


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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