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Просмотр по автору "Krylova E.S."

Просмотр по автору "Krylova E.S."

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  • Design, synthesis, antibacterial activity and toxicity of novel quaternary ammonium compounds based on pyridoxine and fatty acids 
    Sapozhnikov S.V.; Sabirova A.E.; Shtyrlin N.V.; Druk A.Y.; Agafonova M.N.; Chirkova M.N.; Kazakova R.R.; Grishaev D.Y.; Nikishova T.V.; Krylova E.S.; Nikitina E.V.; Kayumov A.R.; Shtyrlin Y.G. (2021)
    A diverse series of 43 novel “soft antimicrobials” based on quaternary ammonium pyridoxine derivatives which include six-membered acetals and ketals of pyridoxine bound via cleavable linker moieties (amide, ester) with a ...
  • Novel acetylcholinesterase inhibitors based on uracil moiety for possible treatment of Alzheimer disease 
    Semenov V.E.; Zueva I.V.; Mukhamedyarov M.A.; Lushchekina S.V.; Petukhova E.O.; Gubaidullina L.M.; Krylova E.S.; Saifina L.F.; Lenina O.A.; Petrov K.A. (2020)
    © 2020 by the authors In this study, novel derivatives based on 6-methyluracil and condensed uracil were synthesized, namely, 2,4-quinazoline-2,4-dione with ω-(ortho-nitrilebenzylethylamino) alkyl chains at the N atoms of ...
  • Novel bis-ammonium salts of pyridoxine: Synthesis and antimicrobial properties 
    Shtyrlin N.V.; Pugachev M.V.; Sapozhnikov S.V.; Garipov M.R.; Vafina R.M.; Grishaev D.Y.; Pavelyev R.S.; Kazakova R.R.; Agafonova M.N.; Iksanova A.G.; Lisovskaya S.A.; Zeldi M.I.; Krylova E.S.; Nikitina E.V.; Sabirova A.E.; Kayumov A.R.; Shtyrlin Y.G. (2020)
    © 2020 by the authors. A series of 108 novel quaternary bis-ammonium pyridoxine derivatives carrying various substituents at the quaternary nitrogen’s and acetal carbon was synthesized. Thirteen compounds exhibited ...
  • Thiacalixarene based quaternary ammonium salts as promising antibacterial agents 
    Padnya P.L.; Terenteva O.S.; Akhmedov A.A.; Iksanova A.G.; Shtyrlin N.V.; Nikitina E.V.; Krylova E.S.; Shtyrlin Y.G.; Stoikov I.I. (2021)
    The search for new antibacterial and antiseptic drugs is an urgent problem due to the resistance of microorganisms to existing drugs. In this work, for the first time, the design of antibacterial and bactericidal agents ...

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