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Browsing by Author "Khaibrakhmanova D."

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Binding constants of drug-albumin complexes from DSC measurements

Khaibrakhmanova D.; Nikiforova A.; Sedov I. (2021)

The DSC technique is applied for quantification of the thermodynamic binding constants in protein-ligand systems. For this purpose, the thermograms of protein denaturation are recorded at different ligand concentrations. ...
Binding constants of substituted benzoic acids with bovine serum albumin

Khaibrakhmanova D.; Nikiforova A.; Sedov I. (2020)

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Experimental data on the affinity of various substances to albumin are essential for the development of empirical models to predict plasma binding of drug candidates. ...
Corrigendum for “Development of Abraham Model Correlations for Solute Transfer into Both 2-Propoxyethanol and 2-Isopropoxyethanol at 298.15 K” (Journal of Molecular Liquids (2017) 241 (730) (S0167732217325199) (10.1016/j.molliq.2017.06.079))

Sedov I.; Khaibrakhmanova D.; Hart E.; Grover D.; Zettl H.; Koshevarova V.; Dai C.; Zhang S.; Schmidt A.; Acree W.; Abraham M. (2017)

© 2017 Elsevier B.V. A typographical error is corrected in Eq. (8) of the published paper.
Development of Abraham model correlations for solute transfer into both 2-propoxyethanol and 2-isopropoxyethanol at 298.15 K

Sedov I.; Khaibrakhmanova D.; Hart E.; Grover D.; Zettl H.; Koshevarova V.; Dai C.; Zhang S.; Schmidt A.; Acree W.; Abraham M. (2015)

© 2015 Elsevier B.V. All rights reserved. Infinite dilution activity coefficients (γ∞) were measured at 298 K for 9 different aliphatic hydrocarbons (alkanes, cycloalkanes, alkenes), 7 different aromatic compounds (benzene, ...
Evaluation of the binding properties of drugs to albumin from DSC thermograms

Sedov I.; Nikiforova A.; Khaibrakhmanova D. (2020)

© 2020 Elsevier B.V. There is a demand in rapid and robust methods to determine the affinity of drugs to receptors, enzymes, and transport proteins. Differential scanning calorimetry (DSC) is a common method to prove the ...

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Browsing by Author "Khaibrakhmanova D."

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