Просмотр по теме "Head and neck cancer"

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Identification of evolutionarily conserved DNA damage response genes that alter sensitivity to cisplatin

Gaponova A.; Deneka A.; Beck T.; Liu H.; Andrianov G.; Nikonova A.; Nicolas E.; Einarson M.; Golemis E.; Serebriiskii I. (2017)

Ovarian, head and neck, and other cancers are commonly treated with cisplatin and other DNA damaging cytotoxic agents. Altered DNA damage response (DDR) contributes to resistance of these tumors to chemotherapies, some ...
Phospho-<sup>T356</sup>RB1 predicts survival in HPV-negative squamous cell carcinoma of the head and neck

Beck T.; Kaczmar J.; Handorf E.; Nikonova A.; Dubyk C.; Peri S.; Lango M.; Ridge J.; Serebriiskii I.; Burtness B.; Golemis E.; Mehra R. (2015)

Locally advanced squamous cell carcinoma of the head and neck (SCCHN) that is not associated with human papillomavirus (HPV) has a poor prognosis in contrast to HPV-positive disease. To better understand the importance of ...
Synthetic lethal targeting of mitotic checkpoints in HPV-negative head and neck cancer

Deneka A.; Einarson M.; Bennett J.; Nikonova A.; Elmekawy M.; Zhou Y.; Lee J.; Burtness B.; Golemis E. (2020)

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Head and neck squamous cell carcinomas (HNSCC) affect more than 800,000 people annually worldwide, causing over 15,000 deaths in the US. Among HNSCC cancers, human ...

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