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Browsing by Author "Hausenloy D."

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From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on “New frontiers in cardiovascular research”

Cabrera-Fuentes H.; Aragones J.; Bernhagen J.; Boening A.; Boisvert W.; Bøtker H.; Bulluck H.; Cook S.; Di Lisa F.; Engel F.; Engelmann B.; Ferrazzi F.; Ferdinandy P.; Fong A.; Fleming I.; Gnaiger E.; Hernández-Reséndiz S.; Kalkhoran S.; Kim M.; Lecour S.; Liehn E.; Marber M.; Mayr M.; Miura T.; Ong S.; Peter K.; Sedding D.; Singh M.; Suleiman M.; Schnittler H.; Schulz R.; Shim W.; Tello D.; Vogel C.; Walker M.; Li Q.; Yellon D.; Hausenloy D.; Preissner K. (2016)

© 2016, The Author(s).In this meeting report, particularly addressing the topic of protection of the cardiovascular system from ischemia/reperfusion injury, highlights are presented that relate to conditioning strategies ...
Full left ventricular coverage is essential for the accurate quantification of the area-at-risk by T1 and T2 mapping

Bulluck H.; Bryant J.; Lim M.; Tan X.; Ramlall M.; Francis R.; Kotecha T.; Cabrera-Fuentes H.; Knight D.; Fontana M.; Moon J.; Hausenloy D. (2017)

© 2017 The Author(s). T2-weighted cardiovascular magnetic resonance (CMR) using a 3-slice approach has been shown to accurately quantify the edema-based area-at-risk (AAR) in ST-segment elevation myocardial infarction ...
FURIN inhibition reduces vascular remodeling and atherosclerotic lesion progression in mice

Yakala G.; Cabrera-Fuentes H.; Crespo-Avilan G.; Rattanasopa C.; Burlacu A.; George B.; Anand K.; Mayan D.; Corlianò M.; Hernández-Reséndiz S.; Wu Z.; Schwerk A.; Tan A.; Trigueros-Motos L.; Chèvre R.; Chua T.; Kleemann R.; Liehn E.; Hausenloy D.; Ghosh S.; Singaraja R. (2019)

© 2019 American Heart Association, Inc. Objective - Atherosclerotic coronary artery disease is the leading cause of death worldwide, and current treatment options are insufficient. Using systems-level network cluster ...
Immune cells as targets for cardioprotection: new players and novel therapeutic opportunities

Andreadou I.; Cabrera-Fuentes H.; Devaux Y.; Frangogiannis N.; Frantz S.; Guzik T.; Liehn E.; Gomes C.; Schulz R.; Hausenloy D. (2019)

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2019. For permissions, please email: journals.permissions@oup.com. New therapies are required to reduce myocardial infarct ...
Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery

Hausenloy D.; Barrabes J.; Bøtker H.; Davidson S.; Di Lisa F.; Downey J.; Engstrom T.; Ferdinandy P.; Carbrera-Fuentes H.; Heusch G.; Ibanez B.; Iliodromitis E.; Inserte J.; Jennings R.; Kalia N.; Kharbanda R.; Lecour S.; Marber M.; Miura T.; Ovize M.; Perez-Pinzon M.; Piper H.; Przyklenk K.; Schmidt M.; Redington A.; Ruiz-Meana M.; Vilahur G.; Vinten-Johansen J.; Yellon D.; Garcia-Dorado D. (2016)

© 2016, The Author(s).To commemorate the auspicious occasion of the 30th anniversary of IPC, leading pioneers in the field of cardioprotection gathered in Barcelona in May 2016 to review and discuss the history of IPC, its ...
Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside

Cabrera-Fuentes H.; Alba-Alba C.; Aragones J.; Bernhagen J.; Boisvert W.; Bøtker H.; Cesarman-Maus G.; Fleming I.; Garcia-Dorado D.; Lecour S.; Liehn E.; Marber M.; Marina N.; Mayr M.; Perez-Mendez O.; Miura T.; Ruiz-Meana M.; Salinas-Estefanon E.; Ong S.; Schnittler H.; Sanchez-Vega J.; Sumoza-Toledo A.; Vogel C.; Yarullina D.; Yellon D.; Preissner K.; Hausenloy D. (2016)

© 2015, The Author(s). Recent advances in basic cardiovascular research as well as their translation into the clinical situation were the focus at the last “New Frontiers in Cardiovascular Research meeting”. Major topics ...
Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside

Cabrera-Fuentes H.; Alba-Alba C.; Aragones J.; Bernhagen J.; Boisvert W.; Bøtker H.; Cesarman-Maus G.; Fleming I.; Garcia-Dorado D.; Lecour S.; Liehn E.; Marber M.; Marina N.; Mayr M.; Perez-Mendez O.; Miura T.; Ruiz-Meana M.; Salinas-Estefanon E.; Ong S.; Schnittler H.; Sanchez-Vega J.; Sumoza-Toledo A.; Vogel C.; Yarullina D.; Yellon D.; Preissner K.; Hausenloy D. (2016)

Recent advances in basic cardiovascular research as well as their translation into the clinical situation were the focus at the last "New Frontiers in Cardiovascular Research meeting". Major topics included the characterization ...
Mitochondrial fusion and fission proteins as novel therapeutic targets for treating cardiovascular disease

Ong S.; Kalkhoran S.; Cabrera-Fuentes H.; Hausenloy D. (2015)

© 2015 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license. The past decade has witnessed a number of exciting developments in the field of mitochondrial dynamics - a phenomenon ...
Quantifying the area-at-risk of myocardial infarction in-vivo using arterial spin labeling cardiac magnetic resonance

Dongworth R.; Campbell-Washburn A.; Cabrera-Fuentes H.; Bulluck H.; Roberts T.; Price A.; Hernández-Reséndiz S.; Ordidge R.; Thomas D.; Yellon D.; Lythgoe M.; Hausenloy D. (2017)

© The Author(s) 2017.T2-weighted cardiovascular magnetic resonance (T2-CMR) of myocardial edema can quantify the area-at-risk (AAR) following acute myocardial infarction (AMI), and has been used to assess myocardial salvage ...
RNase1 prevents the damaging interplay between extracellular RNA and tumour necrosis factor-α in cardiac ischaemia/reperfusion injury

Cabrera-Fuentes H.; Ruiz-Meana M.; Simsekyilmaz S.; Kostin S.; Inserte J.; Saffarzadeh M.; Galuska S.; Vijayan V.; Barba I.; Barreto G.; Fischer S.; Lochnit G.; Ilinskaya O.; Baumgart-Vogt E.; Böning A.; Lecour S.; Hausenloy D.; Liehn E.; Garcia-Dorado D.; Schlüter K.; Preissner K. (2014)

© Schattauer 2014 Despite optimal therapy, the morbidity and mortality of patients presenting with an acute myocardial infarction (M1) remain significant, and the initial mechanistic trigger of myocardial “ischaemia/reperfusion ...
Role of macrophages in cardioprotection

Yap J.; Cabrera-Fuentes H.; Irei J.; Hausenloy D.; Boisvert W. (2019)

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. Cardiovascular diseases are the leading cause of mortality worldwide. It is widely known that non-resolving inflammation results in atherosclerotic conditions, which ...
Role of the MPTP in conditioning the heart - Translatability and mechanism

Ong S.; Dongworth R.; Cabrera-Fuentes H.; Hausenloy D. (2015)

© 2014 The Authors. British Journal of Pharmacology published by John Wiley Sons Ltd on behalf of The British Pharmacological Society. Mitochondria have long been known to be the gatekeepers of cell fate. This is particularly ...
Role of the MPTP in conditioning the heart - translatability and mechanism

Ong S.; Dongworth R.; Cabrera-Fuentes H.; Hausenloy D. (2015)

© 2014 The Authors. Mitochondria have long been known to be the gatekeepers of cell fate. This is particularly so in the response to acute ischaemia-reperfusion injury (IRI). Following an acute episode of sustained myocardial ...
Targeting mitochondrial fission using Mdivi-1 in A clinically relevant large animal model of acute myocardial infarction: A pilot study

Ong S.; Kwek X.; Katwadi K.; Hernandez-Resendiz S.; Crespo-Avilan G.; Ismail N.; Lin Y.; Yap E.; Lim S.; Myu Mai Ja K.; Ramachandra C.; Tee N.; Toh J.; Shim W.; Wong P.; Cabrera-Fuentes H.; Hausenloy D. (2019)

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. Background: New treatments are needed to reduce myocardial infarct size (MI) and prevent heart failure (HF) following acute myocardial infarction (AMI), which are ...

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Browsing by Author "Hausenloy D."

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