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Browsing by Author "Gumerova A."

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C-kit and desmin-positive cells in expression in islets of pancreas during alloxan diabetes in rats.

Kaligin M.; Plushkina A.; Titova A.; Titova M.; Gumerova A.; Kiassov A. (2013)

Nowadays there are findings that C-kit-positive and desmin-positive stellate cells help to regenerate endocrine part of pancreas. But still it is unknown about their role and the way of differentiation of these cells during ...
C-kit-positive pancreas islets cell of rats pancreas as a endocrine cells progenitor during alloxan diabetes

Plushkina A.; Kaligin M.; Andreeva D.; Titova A.; Valeeva I.; Demyanov A.; Gumerova A.; Kiassov A. (2012)

One of the most common markers for stem cells in pancreas is the stem cell factor receptor C-kit (CD117) that plays a main role in differentiation of progenitor endocrine cells of pancreas islets in prenatal development ...
Can pancreas be the source of hepatocytes?

Abdulkhakova A.; Abdulkhakov S.; Titova M.; Saifullina K.; Gumerova A.; Kiasov A. (2012)

The possibility of hepatocytes differentiation from pancreatic cells is discussed in the review. Both liver and pancreas develop from endoderm so there could be a common stem cell giving rise to both pancreatic and liver ...
CCL27: Novel cytokine with potential role in pathogenesis of multiple sclerosis

Khaiboullina S.; Gumerova A.; Khafizova I.; Martynova E.; Lombardi V.; Bellusci S.; Rizvanov A. (2015)

© 2015 Svetlana F. Khaiboullina et al. Multiple sclerosis (MS) is an autoimmune and neurodegenerative disease of unknown etiology. Leukocyte infiltration of brain tissue and the subsequent inflammation, demyelination, ...
Changes of liver microstructure after partial hepatectomy in rats

Gazizov I.; Kaligin M.; Andreeva D.; Yilmaz T.; Gumerova A.; Kiassov A. (2013)

Ability of mammalian liver to regenerate is one of the favorite examples of "regenerative medicine". At the same time liver regeneration can not be viewed as a simple hypertrophy, it must have some appropriate steps. ...
Changes of the inflammatory activity and fibrosis in patients with alcoholic liver cirrhosis after autologous hematopoietic stem cell transplantation

Burganova G.; Abdulkhakov S.; Gumerova A.; Gazizov I.; Yilmaz T.; Titova M.; Odintcova A.; Kiassov A. (2012)

Evaluation of treatment results of chronic liver diseases should be made on the basis of morphological analysis of liver biopsies. The aim of our study was to investigate the effect of autologous hematopoietic stem cell ...
Comparison of different methods of rat hepatic stellate cells isolation, labeling and transplantation

Shafigullina A.; Trondin A.; Burganova G.; Titova A.; Mavlikeev M.; Sharipova E.; Tabanakova A.; Gazizov I.; Kaligin M.; Titova M.; Rizvanov A.; Gumerova A.; Kiassov A. (2013)

Nowadays more and more attention is turned to hepatic stellate cells (HSC) and their role in liver regeneration. Nonetheless there are several methodological questions, for example, methods of HSC isolation, their labeling ...
Effect of Adenoviral Transduction of Hepatic Stellate Cells with Adv5-optHGF-RFP on their Phenotype

Shafigullina A.; Zaikina E.; Garanina E.; Sakhapov D.; Titova A.; Mavlikeev M.; Rizvanov A.; Gumerova A.; Kiassov A. (2017)

© 2016, Springer Science+Business Media New York.Adenovirus is a promising gene delivery vector that has a high efficiency and relative simplicity of construction. These advantages make this system attractive for diverse ...
Effect of Curcumin and Gliotoxin on Rat Liver Myofibroblast Culture

Shafigullina A.; Mijanovic O.; Prottoy R.; Zhuravleva M.; Gomzikova M.; Gumerova A.; Rizvanov A.; Kiyasov A. (2018)

© 2017, Springer Science+Business Media, LLC, part of Springer Nature. Since the 1990s, when it was demonstrated by Hammel and others that liver fibrosis is reversible, researchers and physicians actively search for new ...
Hepatic stellate cells - Regional stem cells of the liver or a component of microenvironment?

Shafigullina A.; Gumerova A.; Kiassov A. (2016)

For years, it is debated about the nature and localization of stem cell of the liver. In recent years, a particular interest is paid to hepatic stellate cells. According to the conducted researches, these cells are actively ...
Hepatic stellate cells stimulate liver regeneration after partial hepatectomy under inhibition of hepatocyte proliferation

Titova A.; Burganova G.; Sharipova E.; Pevnev G.; Mavlikeev M.; Gazizov I.; Galyavieva A.; Shafigullina A.; Kaligin M.; Titova M.; Gumerova A.; Kiassov A. (2014)

Most of the fundamental studies in the field of developing new methods for treating liver diseases in regenerative medicine are performed with haematopoietic and mesenchymal stem cells. At the same time more and more ...
Histopathological Analysis of Skeletal Muscle Biopsy of Patient with Peripheral Arterial Disease before and after Peripheral Blood Stem Cells Intramuscular Injection

Mavlikeev M.; Plotnikov M.; Maximov A.; Murtazin A.; Gafiatullina G.; Titova A.; Gazizov I.; Deev R.; Gumerova A.; Kiyasov A. (2017)

© 2016, Springer Science+Business Media New York.Peripheral arterial diseases are characterized by a progressing tissue ischemia which results in the invalidization of patients. The aim of our research was to study the ...
Influence of the human umbilical cord blood mononuclear cells transplantation on regeneration of the rat kidney after unilateral ureteral obstruction

Tabanakova A.; Yilmaz T.; Fairushina I.; Gumerova A.; Kiassov A. (2013)

Stem cell therapy may provide effective and patogenetically proved treatment of chronic kidney disease caused by interstitial fibrosis after tubule damage. It was reported that transplanted bone marrow stem cells participate ...
Liver Cells Proliferation and Apoptosis in Patients with Alcoholic Liver Disease After Autologous Hematopoietic Stem Cell Transplantation

Burganova G.; Abdulkhakov S.; Gazizov I.; Gumerova A.; Titova M.; Odintcova A.; Kiassov A. (2017)

© 2016, Springer Science+Business Media New York.Alcoholic liver disease is a huge medical and social problem that leads to liver fibrosis, cirrhosis, and hepatocellular carcinoma. Unfortunately, the last stages of the ...
Long-term results of autologous peripheral blood hematopoietic stem cell transplantation in patients with peripheral arterial diseases

Plotnikov M.; Maksimov A.; Mavlikeev M.; Gazizov I.; Tamakova V.; Cherepnev G.; Shamsutdinova I.; Gumerova A.; Kiassov A. (2013)

The aim of our work was to assess long-term results of autologous peripheral blood hematopoietic stem cell application in patients with peripheral arterial diseases. Peripheral blood hematopoietic stem cells mobilized by ...
Native and Activated Hepatic Stellate Cells Stimulate Liver Regeneration in Rats After Partial Hepatectomy and 2-Acetylaminofluorene Injection

Zaikina E.; Shafigullina A.; Titova A.; Burganova G.; Pevnev G.; Mavlikeev M.; Shahmardanova S.; Titova M.; Rizvanov A.; Gumerova A.; Kiassov A. (2017)

© 2016, Springer Science+Business Media New York.One the current challenges of modern hepatology is to find new approaches to stimulate liver regeneration and to find new methods for liver disease treatment. Cell therapies, ...
Participation of the mononuclear cells of the cord blood in the physiologic regeneration of the rat kidney

Yilmaz T.; Mavlikeeva A.; Gumerova A.; Andreeva D.; Fairushina I.; Kiiasov A. (2012)

Nowadays ability to use hematopoietic stem cells for treatment of various diseases, including kidney pathology, is widely investigated. Umbilical cord blood as the source of hematopoietic stem cells becomes more and more ...
Population Dynamics of MafA-Positive Cells During Ontogeny of Human Pancreas

Kaligin M.; Pliushkina A.; Titova A.; Titova M.; Gumerova A.; Kiassov A. (2017)

© 2016, Springer Science+Business Media New York.Diverse transcription factors influencing cell differentiation are often chosen as markers of β cell progenitors. One of these transcription factors is MafA, which according ...
Possible directions of human cord blood mononuclear cells differentiation in the regenerating rat liver

Andreeva D.; Gazizov I.; Ylmaz T.; Kaligin M.; Gumerova A.; Kiyasov A. (2013)

It is known that human cord blood hematopoietic stem cells (HSC) are able to differentiate into hepatocytes. This ability can be widely used in treatment of various liver diseases. However, there are some genetic diseases ...
Transplanted hepatic stellate cells participate in liver regeneration after partial hepatectomy without risk of hepatic fibrosis

Shafigullina A.; Gumerova A.; Trondin A.; Titova M.; Gazizov I.; Burganova G.; Kaligin M.; Andreeva D.; Rizvanov A.; Muhamedov A.; Kiassov A. (2012)

Hepatic stellate cells are considered as one of the potential stem cells candidates in the liver. The aim of our work was to study the probability of hepatic stellate cells transplantation to rats after partial hepatectomy, ...

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Browsing by Author "Gumerova A."

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