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Browsing by Author "Grishaev D.Y."

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Design, synthesis, antibacterial activity and toxicity of novel quaternary ammonium compounds based on pyridoxine and fatty acids

Sapozhnikov S.V.; Sabirova A.E.; Shtyrlin N.V.; Druk A.Y.; Agafonova M.N.; Chirkova M.N.; Kazakova R.R.; Grishaev D.Y.; Nikishova T.V.; Krylova E.S.; Nikitina E.V.; Kayumov A.R.; Shtyrlin Y.G. (2021)

A diverse series of 43 novel “soft antimicrobials” based on quaternary ammonium pyridoxine derivatives which include six-membered acetals and ketals of pyridoxine bound via cleavable linker moieties (amide, ester) with a ...
Novel bis-ammonium salts of pyridoxine: Synthesis and antimicrobial properties

Shtyrlin N.V.; Pugachev M.V.; Sapozhnikov S.V.; Garipov M.R.; Vafina R.M.; Grishaev D.Y.; Pavelyev R.S.; Kazakova R.R.; Agafonova M.N.; Iksanova A.G.; Lisovskaya S.A.; Zeldi M.I.; Krylova E.S.; Nikitina E.V.; Sabirova A.E.; Kayumov A.R.; Shtyrlin Y.G. (2020)

© 2020 by the authors. A series of 108 novel quaternary bis-ammonium pyridoxine derivatives carrying various substituents at the quaternary nitrogen’s and acetal carbon was synthesized. Thirteen compounds exhibited ...
Supramolecular amphiphiles based on pillar[5]arene and meroterpenoids: Synthesis, self-association and interaction with floxuridine

Akhmedov A.A.; Shurpik D.N.; Padnya P.L.; Khadieva A.I.; Gamirov R.R.; Panina Y.V.; Gazizova A.F.; Grishaev D.Y.; Plemenkov V.V.; Stoikov I.I. (2021)

In recent years, meroterpenoids have found wide biomedical application due to their synthetic availability, low toxicity, and biocompatibility. However, these compounds are not used in targeted drug delivery systems due ...
Synthesis, antitumor activity and structure-activity studies of novel pyridoxine-based bioisosteric analogs of estradiol

Pugachev M.V.; Pavelyev R.S.; Nguyen T.N.T.; Gabbasova R.R.; Bulatov T.M.; Iksanova A.G.; Aljondi B.; Bondar O.V.; Grishaev D.Y.; Yamaleeva Z.R.; Kataeva O.N.; Nikishova T.V.; Balakin K.V.; Shtyrlin Y.G. (2021)

A new efficient approach to the synthesis of 6-alkenyl substituted pyridoxine derivatives has been developed. A series of 31 novel alkenyl pyridoxine derivatives, stilbene-based bioisosteric analogs of estradiol, were ...

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Browsing by Author "Grishaev D.Y."

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