Browsing by Author "Fomum Z."

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Heterocycles of biological importance: Part 6. The formation of novelbiologically active pyrimido[1,2-a]benzimid-azoles from electron deficientalkynes and 2-aminobenzimidazoles

Wahe H.; Asobo P.; Cherkasov R.; Nkengfack A.; Folefoc G.; Fomum Z.; Doepp D. (2003)

2-Aminobenzimidazole (1a) and its 5,6-dimethyl derivative 1b react with phenylpropynenitrile (2) to give 2-amino-4-phenylpyrimido[1,2-a]benzimidazoles 8a,b in excellent yields. Of these compounds, 2-amino-7,8-dimethyl-4- ...
Heterocycles of biological importance: Part 7. Synthesis of biologicallyactive pyrimido[2,1-b]benzothiazoles from acetylenic acids and2-aminobenzothiazoles

Wahe H.; Mbafor J.; Nkengfack A.; Fomum Z.; Cherkasov R.; Sterner O.; Doepp D. (2003)

Conjugate addition of the imino nitrogen of 2-aminobenzothiazoles 1 to the alkyne β-carbon atom of acetylenic acids 2 followed by ring closure gives rise to novel 2H-pyrimido[2,1-b]-benzothiazol-2-ones in good yield.

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