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Browsing by Author "Fedotova V."

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Analysis of recombinant VEGF gene expression by genetically modified umbilical cord blood mononuclear cells in experiment in vivo

Mukhamedshina Y.; Solovieva V.; Salafutdinov I.; Cherenkova E.; Fedotova V.; Safiullov Z.; Izmailov A.; Sharifullina G.; Abdulhakov S.; Kaligin M.; Bashirov F.; Muhamediarov M.; Shmarov M.; Naroditskii B.; Kiiasov A.; Rizvanov A.; Islamov R. (2012)

To obtain a significant therapeutic effect transplanted genetically modified cells should have an enhanced ability to survive and active expression of the therapeutic gene. In this paper, by using immunofluorescent staining ...
Analysis of the efficiency of gene-cell therapy in transgenic mice with amyotrophic lateral sclerosis phenotype

Mukhamedyarov M.; Rizvanov A.; Safiullov Z.; Izmailov A.; Sharifullina G.; Solovieva V.; Fedotova V.; Salafutdinov I.; Cherenkova E.; Bashirov F.; Kaligin M.; Abdulkhakov S.; Shmarov M.; Logunov D.; Naroditsky B.; Kiyasov A.; Zefirov A.; Islamov R. (2013)

Amyotrophic lateral sclerosis is a neurodegenerative disease characterized by progressive death of cerebral and spinal motorneurons. Using behavioral tests we studied the efficiency of gene-cell therapy in SOD1 G93A ...
Generation of recombinant adenoviral vectors encoding neural cell adhesion molecules ncam1, ncam2 and l1cam

Fedotova V.; Cherenkova E.; Islamov R.; Rizvanov A. (2013)

To succed in gene therapy it is necessary to observe few basic conditions, such as targeted delivery of the therapeutic gene into the target organ and its effective expression. Nowadays targeted delivery of therapeutic ...
Generation of recombinant adenoviruses and lentiviruses expressing angiogenic and neuroprotective factors using Gateway cloning technology

Cherenkova E.; Fedotova V.; Borisov M.; Islamov R.; Rizvanov A. (2012)

The critical aspect in gene and gene-cell therapy is to find an optimal vector - a carrier of genetic information. Viruses represent a natural biological system for gene transfer into eukaryotic cells. One of the most ...
Symptomatic improvement, increased life-span and sustained cell homing in amyotrophic lateral sclerosis after transplantation of human umbilical cord blood cells genetically modified with adeno-viral vectors expressing a neuro-protective factor and a neural cell adhesion molecule

Islamov R.; Rizvanov A.; Mukhamedyarov M.; Salafutdinov I.; Garanina E.; Fedotova V.; Solovyeva V.; Mukhamedshina Y.; Safiullov Z.; Izmailov A.; Guseva D.; Zefirov A.; Kiyasov A.; Palotás A. (2015)

© 2015 Bentham Science Publishers. Amyotrophic lateral sclerosis (ALS) is an incurable, chronic, fatal neuro-degenerative disease characterized by progressive loss of moto-neurons and paralysis of skeletal muscles. ...
Tandem Delivery of Multiple Therapeutic Genes Using Umbilical Cord Blood Cells Improves Symptomatic Outcomes in ALS

Islamov R.; Rizvanov A.; Fedotova V.; Izmailov A.; Safiullov Z.; Garanina E.; Salafutdinov I.; Sokolov M.; Mukhamedyarov M.; Palotás A. (2016)

© 2016 Springer Science+Business Media New YorkCurrent treatment options of chronic, progressive degenerative neuropsychiatric conditions offer only marginal efficacy, and there is no therapy which arrests or even reverses ...
Tandem Delivery of Multiple Therapeutic Genes Using Umbilical Cord Blood Cells Improves Symptomatic Outcomes in ALS

Islamov R.; Rizvanov A.; Fedotova V.; Izmailov A.; Safiullov Z.; Garanina E.; Salafutdinov I.; Sokolov M.; Mukhamedyarov M.; Palotás A. (2017)

© 2016, Springer Science+Business Media New York. Current treatment options of chronic, progressive degenerative neuropsychiatric conditions offer only marginal efficacy, and there is no therapy which arrests or even ...

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Browsing by Author "Fedotova V."

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