Browsing by Author "Daly M."

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Interaction of germline variants in a family with a history of early-onset clear cell renal cell carcinoma

Nicolas E.; Demidova E.; Iqbal W.; Serebriiskii I.; Vlasenkova R.; Ghatalia P.; Zhou Y.; Rainey K.; Forman A.; Dunbrack R.; Golemis E.; Hall M.; Daly M.; Arora S. (2019)

© 2019 The Authors. Molecular Genetics & Genomic Medicine published by Wiley Periodicals, Inc. Background: Identification of genetic factors causing predisposition to renal cell carcinoma has helped improve screening, ...
Systematic evaluation of underlying defects in DNA repair as an approach to case-only assessment of familial prostate cancer

Nicolas E.; Arora S.; Zhou Y.; Serebriiskii I.; Andrake M.; Handorf E.; Bodian D.; Vockley J.; Dunbrack R.; Ross E.; Egleston B.; Hall M.; Golemis E.; Giri V.; Daly M. (2015)

Risk assessment for prostate cancer is challenging due to its genetic heterogeneity. In this study, our goal was to develop an operational framework to select and evaluate gene variants that may contribute to familial ...

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