Browsing by Author "Cymerman I."

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Production and characterization of recombinant protein preparations of Endonuclease G-homologs from yeast, C. elegans and humans

Kieper J.; Lauber C.; Gimadutdinow O.; Urbaǹska A.; Cymerman I.; Ghosh M.; Szczesny B.; Meiss G. (2010)

Nuc1p, CPS-6, EndoG and EXOG are evolutionary conserved mitochondrial nucleases from yeast, Caenorhabditis elegans and humans, respectively. These enzymes play an important role in programmed cell death as well as mitochondrial ...
Structural and functional characterization of mitochondrial EndoG, a sugar non-specific nuclease which plays an important role during apoptosis

Schäfer P.; Scholz S.; Gimadutdinow O.; Cymerman I.; Bujnicki J.; Ruiz-Carrillo A.; Pingoud A.; Meiss G. (2004)

Combining sequence analysis, structure prediction, and site-directed mutagenesis, we have investigated the mechanism of catalysis and substrate binding by the apoptotic mitochondrial nuclease EndoG, which belongs to the ...

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