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Browsing by Author "Beck T."

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An improved method of delivering a sclerosing agent for the treatment of malignant pleural effusion

Beck T.; Deneka A.; Chai L.; Kanach C.; Johal P.; Alvarez N.; Boumber Y.; Golemis E.; Laub G. (2019)

© 2019 The Author(s). Background: Malignant pleural effusion (MPE) is a devastating sequela associated with cancer. Talc pleurodesis is a common treatment strategy for MPE but has been estimated to be unsuccessful in up ...
Anti-Müllerian Hormone Signaling Regulates Epithelial Plasticity and Chemoresistance in Lung Cancer

Beck T.; Korobeynikov V.; Kudinov A.; Georgopoulos R.; Solanki N.; Andrews-Hoke M.; Kistner T.; Pépin D.; Donahoe P.; Nicolas E.; Einarson M.; Zhou Y.; Boumber Y.; Proia D.; Serebriiskii I.; Golemis E. (2016)

© 2016 The Author(s)Anti-Müllerian hormone (AMH) and its type II receptor AMHR2, both previously thought to primarily function in gonadal tissue, were unexpectedly identified as potent regulators of transforming growth ...
Case report: Reinitiating pembrolizumab treatment after small bowel perforation

Beck T.; Kudinov A.; Dulaimi E.; Boumber Y. (2019)

© 2019 The Author(s). Background: Immune checkpoint inhibitors (ICIs) have emerged as paradigm shifting treatment options for a number of cancers. Six antibodies targeting the immune checkpoint proteins programmed cell ...
Circulating tumor cell and cell-free RNA capture and expression analysis identify platelet-associated genes in metastatic lung cancer

Beck T.; Boumber Y.; Aggarwal C.; Pei J.; Thrash-Bingham C.; Fittipaldi P.; Vlasenkova R.; Rao C.; Borghaei H.; Cristofanilli M.; Mehra R.; Serebriiskii I.; Alpaugh R. (2019)

© 2019 The Author(s). Background: Circulating tumor cells (CTC) and plasma cell-free RNA (cfRNA) can serve as biomarkers for prognosis and treatment response in lung cancer. One barrier to the selected or routine use of ...
EGFR and RB1 as dual biomarkers in HPV-negative head and neck cancer

Beck T.; Georgopoulos R.; Shagisultanova E.; Sarcu D.; Handorf E.; Dubyk C.; Lango M.; Ridge J.; Astsaturov I.; Serebriiskii I.; Burtness B.; Mehra R.; Golemis E. (2016)

© 2016 American Association for Cancer Research.Clinical decision making for human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC) is predominantly guided by disease stage and anatomic location, ...
Identification of evolutionarily conserved DNA damage response genes that alter sensitivity to cisplatin

Gaponova A.; Deneka A.; Beck T.; Liu H.; Andrianov G.; Nikonova A.; Nicolas E.; Einarson M.; Golemis E.; Serebriiskii I. (2017)

Ovarian, head and neck, and other cancers are commonly treated with cisplatin and other DNA damaging cytotoxic agents. Altered DNA damage response (DDR) contributes to resistance of these tumors to chemotherapies, some ...
Musashi-2 (MSI2) supports TGF-β signaling and inhibits claudins to promote non-small cell lung cancer (NSCLC) metastasis

Kudinov A.; Deneka A.; Nikonova A.; Beck T.; Ahn Y.; Liu X.; Martinez C.; Schultz F.; Reynolds S.; Yang D.; Cai K.; Yaghmour K.; Baker K.; Egleston B.; Nicolas E.; Chikwem A.; Andrianov G.; Singh S.; Borghaei H.; Serebriiskii I.; Gibbons D.; Kurie J.; Golemis E.; Boumber Y. (2016)

© 2016, National Academy of Sciences. All rights reserved.Non-small cell lung cancer (NSCLC) has a 5-y survival rate of ∼16%, with most deaths associated with uncontrolled metastasis. We screened for stem cell identity-related ...
Phospho-<sup>T356</sup>RB1 predicts survival in HPV-negative squamous cell carcinoma of the head and neck

Beck T.; Kaczmar J.; Handorf E.; Nikonova A.; Dubyk C.; Peri S.; Lango M.; Ridge J.; Serebriiskii I.; Burtness B.; Golemis E.; Mehra R. (2015)

Locally advanced squamous cell carcinoma of the head and neck (SCCHN) that is not associated with human papillomavirus (HPV) has a poor prognosis in contrast to HPV-positive disease. To better understand the importance of ...
Tumor-targeted drug conjugates as an emerging novel therapeutic approach in small cell lung cancer (Sclc)

Deneka A.; Golemis E.; Boumber Y.; Beck T. (2019)

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. There are few effective therapies for small cell lung cancer (SCLC), a highly aggressive disease representing 15% of total lung cancers. With median survival <2 ...

Now showing items 1-9 of 9

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Browsing by Author "Beck T."

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