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Browsing by Author "Ayupov R."

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Comparative analysis of mice acetylcholinesterases by functional amino acid residues and molecular screening

Ayupov R.; Andrianov G.; Akberova N. (2015)

In this paper, we have measured the distances between the reference amino acid residues of the acetylcholinesterase (AChE) active site, which showed that the existing three-dimensional models either have no differences or ...
Computational Exploration of Reactivity of 6-Methyluracil/Imidazole-2-Carbaldehyde Oxime Conjugate

Lushchekina S.; Ayupov R.; Semenov V.; Petrov K.; Masson P. (2017)

© 2016, Springer Science+Business Media New York.Molecular docking and ab intio quantum mechanical calculations were used to assess the nucleophilic reactivity of conjugates of 6-methyluracil and imidazole-2-carbaldehyde ...
Diversity and regulation of S-adenosylmethionine dependent methyltransferases in the anhydrobiotic midge

Deviatiiarov R.; Ayupov R.; Laikov A.; Shagimardanova E.; Kikawada T.; Gusev O. (2020)

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Multiple co-localized paralogs of genes in Polypedilum vanderplanki’s genome have strong transcriptional response to dehydration and considered to be a part of ...
Isolation and purification of staphylococcus aureus hibernationpromoting factor inactivating of the ribosome

Ayupov R.; Khusainov I.; Validov S.; Yusupova G.; Yusupov M. (2016)

© 2016, International Journal of Pharmacy and Technology. All rights reserved.In Staphylococcus aureus hibernation-promoting factor (SaHPF) binds to ribosomes depleting translation and turning metabolism of this pathogenic ...
Molecular dynamics of the pyridoxine derivative in the acetylcholinesterase active cavity

Ayupov R.; Akberova N. (2015)

Acetylcholinesterase (AChE) is a key enzyme in central nervous system, responsible for the regulation of nerve impulse transmission through the rapid hydrolysis of the acetylcholine neurotransmitter. In recent years, the ...
NMR assignments of the N-terminal domain of Staphylococcus aureus hibernation promoting factor (SaHPF)

Usachev K.; Ayupov R.; Validov S.; Khusainov I.; Yusupov M. (2017)

© 2017 Springer Science+Business Media B.V. Staphylococcus aureus: hibernation-promoting factor (SaHPF) is a 22.2 kDa stationary-phase protein that binds to the ribosome and turns it to the inactive form favoring survival ...
Prediction of the three-dimensional structure of the protein SaHPF and analysis of its molecular dynamics

Ayupov R.; Akberova N. (2016)

© 2016, International Journal of Pharmacy and Technology. All rights reserved.SaHPF is the protein of gram-positive bacterium Staphylococcus aureus, which is causesa variety of diseases (pneumonia, meningitis, endocarditis, ...
Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF

Khusainov I.; Vicens Q.; Ayupov R.; Usachev K.; Myasnikov A.; Simonetti A.; Validov S.; Kieffer B.; Yusupova G.; Yusupov M.; Hashem Y. (2017)

© 2017 The Authors In bacteria, ribosomal hibernation shuts down translation as a response to stress, through reversible binding of stress-induced proteins to ribosomes. This process typically involves the formation of ...
The fluctuation analysis of conformational mobility for pyridoxine derivatives in the active site of acetylcholinesterase

Ayupov R.; Akberova N. (2016)

© 2016, International Journal of Pharmacy and Technology. All rights reserved.Acetylcholinesterase (AChE) is the main enzyme of the nervous system that is responsible for the regulation of a nerve impulse transfer by a ...

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Browsing by Author "Ayupov R."

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