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Просмотр по автору "Aird K."

Просмотр по автору "Aird K."

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  • HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci 
    Aird K.; Iwasaki O.; Kossenkov A.; Tanizawa H.; Fatkhutdinov N.; Bitler B.; Le L.; Alicea G.; Yang T.; Johnson F.; Noma K.; Zhang R. (2016)
    Cellular senescence is a stable cell growth arrest that is characterized by the silencing of proliferation-promoting genes through compaction of chromosomes into senescence-associated heterochromatin foci (SAHF). Paradoxically, ...
  • Targeting RRM2 and mutant BRAF is a novel combinatorial strategy for melanoma 
    Fatkhutdinov N.; Sproesser K.; Krepler C.; Liu Q.; Brafford P.; Herlyn M.; Aird K.; Zhang R. (2016)
    © 2016 American Association for Cancer Research.The majority of patients with melanoma harbor mutations in the BRAF oncogene, thus making it a clinically relevant target. However, response to mutant BRAF inhibitors (BRAFi) ...

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