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Browsing by Author "Abushik P."

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Cholinergic nociceptive mechanisms in rat meninges and trigeminal Ganglia: Potential implications for migraine pain

Shelukhina I.; Mikhailov N.; Abushik P.; Nurullin L.; Nikolsky E.; Giniatullin R. (2017)

© 2017 Shelukhina, Mikhailov, Abushik, Nurullin, Nikolsky and Giniatullin.Background: Parasympathetic innervation of meninges and ability of carbachol, acetylcholine (ACh) receptor (AChR) agonist, to induce headaches ...
GluN2A subunit-containing NMDA receptors are the preferential neuronal targets of homocysteine

Sibarov D.; Abushik P.; Giniatullin R.; Antonov S. (2016)

© 2016 Sibarov, Abushik, Giniatullin and Antonov.Homocysteine (HCY) is an endogenous redox active amino acid, best known as contributor to various neurodegenerative disorders. Although it is known that HCY can activate ...
Homocysteine-induced membrane currents, calcium responses and changes in mitochondrial potential in rat cortical neurons

Abushik P.; Karelina T.; Sibarov D.; Stepanenko Y.; Giniatullin R.; Antonov S. (2015)

© 2015, Pleiades Publishing, Ltd. Homocysteine, a sulfur-containing amino acid, exerts neurotoxic effects and is involved in the pathogenesis of many neurodegenerative disorders. In contrast to well-studied glutamate ...
Nucleotide homeostasis and purinergic nociceptive signaling in rat meninges in migraine-like conditions

Yegutkin G.; Guerrero-Toro C.; Kilinc E.; Koroleva K.; Ishchenko Y.; Abushik P.; Giniatullina R.; Fayuk D.; Giniatullin R. (2016)

© 2016, Springer Science+Business Media Dordrecht.Extracellular ATP is suspected to contribute to migraine pain but regulatory mechanisms controlling pro-nociceptive purinergic mechanisms in the meninges remain unknown. ...
Pro-nociceptive migraine mediator CGRP provides neuroprotection of sensory, cortical and cerebellar neurons via multi-kinase signaling

Abushik P.; Bart G.; Korhonen P.; Leinonen H.; Giniatullina R.; Sibarov D.; Levonen A.; Malm T.; Antonov S.; Giniatullin R. (2017)

© 2016, © International Headache Society 2016. Background: Blocking the pro-nociceptive action of CGRP is one of the most promising approaches for migraine prophylaxis. The aim of this study was to explore a role for CGRP ...

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Browsing by Author "Abushik P."

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