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2(5H)-Furanone Derivatives as Inhibitors of Staphylococcal Biofilms

Trizna E.; Latypova L.; Kurbangalieva A.; Bogachev M.; Kayumov A. (2016)

© 2016, Springer Science+Business Media New York.The opportunistic bacteria Staphylococcus aureus and Staphylococcus epidermidis often form rigid biofilms on wounds and artificial surfaces and thereby become extremely ...
Antimicrobial effects of sulfonyl derivative of 2(5H)-furanone against planktonic and biofilm associated methicillin-resistant and -susceptible Staphylococcus aureus

Sharafutdinov I.; Trizna E.; Baidamshina D.; Ryzhikova M.; Sibgatullina R.; Khabibrakhmanova A.; Latypova L.; Kurbangalieva A.; Rozhina E.; Klinger-Strobel M.; Fakhrullin R.; Pletz M.; Bogachev M.; Kayumov A.; Makarewicz O. (2017)

© 2017 Sharafutdinov, Trizna, Baidamshina, Ryzhikova, Sibgatullina, Khabibrakhmanova, Latypova, Kurbangalieva,Rozhina, Klinger-Strobel, Fakhrullin, Pletz, Bo gachev, Kayumov and Makarewicz. The gram-positive opportunistic ...
Cocrystallization of diastereomers in the series of 2(5H)-furanone bis-thioethers based on 1,2-phenylenedimethanethiol

Lodochnikova O.; Hoang L.; Zaripova A.; Kayumov A.; Litvinov I.; Kurbangalieva A. (2016)

© 2016, Springer Science+Business Media New York.Crystallization of diastereomeric mixtures of 2(5H)-furanone bis-thioethers, in the molecules of which two unsaturated γ-lactone rings are bound by 1,2-phenylenedimethanethiol ...
Crystallization of racemic 4-arylsulfonyl-2(5H)-furanones: Reproducibility of homochiral associates, conditions for the spontaneous resolution of enantiomers and the formation of racemic compounds, the role of intermolecular interactions

Lodochnikova O.; Voronina Y.; Latypova L.; Krivolapov D.; Kurbangalieva A.; Litvinov I. (2013)

Crystallization of three 4-arylsulfonyl-2(5H)-furanones from chloroform leads to the formation of a conglomerate of sulfone with para-tolyl substituent and racemic crystals of chloro and bromo analogs. The high degree of ...
Electrochemical reduction of mucochloric acid and its 5-alkoxy derivatives

Latypova L.; Yanilkin V.; Kurbangalieva A.; Berdnikov E.; Chmutova G. (2012)

5-Alkoxy-3-chloro-2(5H)-furanones were synthesized by the electrochemical reduction of 5-alkoxy derivatives of mucochloric acid in acetonitrile on the lead electrode in the presence of acetic acid as a proton donor. A ...
First example of the synthesis of S,O-macroheterocycle based on 2(5H)-furanone and 2,2´-oxydiethanethiol

Kurbangalieva A.; Hoang L.; Lodochnikova O.; Kuzmicheva M.; Pradipta A.; Tanaka K.; Chmutova G. (2016)

© 2016, Springer Science+Business Media New York.A base-catalyzed reaction of 3,4-dichloro-5-methoxy- and 3,4-dichloro-5-ethoxy-2(5H)-furanones with 2,2´-oxydiethanethiol gave thiols and bis-thioethers of 2(5H)-furanone ...
Increasing Susceptibility of Drug-Resistant Candida albicans to Fluconazole and Terbinafine by 2(5H)-Furanone Derivative

Sharafutdinov I.S.; Ozhegov G.D.; Sabirova A.E.; Novikova V.V.; Lisovskaya S.A.; Khabibrakhmanova A.M.; Kurbangalieva A.R.; Bogachev M.I.; Kayumov A.R. (2020)

© 2020 by the authors The frequency of mycoses caused by drug-resistant fungal pathogen Candida albicans has increased drastically over the last two decades. The spread of drug-resistant strains, along with the limitations ...
Mechanism of electrochemical reduction of 5-thio derivatives of 2(5H)-furanone

Latypova L.; Chmutova G.; Kurbangalieva A.; Yanilkin V. (2019)

© 2019, Springer Science+Business Media, Inc. The anionoid elimination of the substituent from position 5 of the lactone ring is the predominant pathway of electrochemical reduction of 5-arylsulfanyl- and 5-arylsulfonyl- ...
Reactions of 2-mercaptoacetic acid with mucochloric acid and its derivatives

Kurbangalieva A.; Devyatova N.; Kosolapova L.; Lodochnikova O.; Berdnikov E.; Litvinov I.; Chmutova G. (2009)

The stable products of reactions of mucochloric acid and some of its ethers with 2-mer-captoacetic acid were synthesized and characterized. The variation of experimental conditions allowed targeted introduction of a sulfur- ...
Synthesis and structure of the products of the reactions of 3-chloro-5-methoxy-4-[(4-methylphenyl)sulfanyl]-2(5H)-furanone with N,N-binucleophilic agents

Kosolapova L.; Kurbangalieva A.; Valiev M.; Lodochnikova O.; Berdnikov E.; Chmutova G. (2013)

Reactions of 3-chloro-5-methoxy-4-[(4-methylphenyl)sulfanyl]-2(5H)-furanone with different nitrogen-containing binucleophilic agents were studied. The reaction with hydrazine monohydrate resulted in the formation of ...
Thio derivatives of 2(5H)-furanone as inhibitors against Bacillus subtilis biofilms

Trizna E.; Khakimullina E.; Latypova L.; Kurbangalieva A.; Sharafutdinov I.; Evtyugin V.; Babynin E.; Bogachev M.; Kayumov A. (2015)

© 2015 Park-media, Ltd. Gram-positive bacteria cause a wide spectrum of infectious diseases, including nosocomial infections. While in the biofilm, bacteria exhibit increased resistance to antibiotics and the human immune ...
Unraveling the molecular mechanism of selective antimicrobial activity of 2(5H)-furanone derivative against Staphylococcus aureus

Sharafutdinov I.; Pavlova A.; Akhatova F.; Khabibrakhmanova A.; Rozhina E.; Romanova Y.; Fakhrullin R.; Lodochnikova O.; Kurbangalieva A.; Bogachev M.; Kayumov A. (2019)

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. Staphylococcus aureus causes various infectious diseases, from skin impetigo to life-threatening bacteremia and sepsis, thus appearing an important target for ...

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