Mitkevich V.; Petrushanko I.; Kretova O.; Spirin P.; Zelenikhin P.; Prassolov V.; Tchurikov N.; Ilinskaya O.; Makarov A.
(2010)
Mutational activation of c-Kit receptor tyrosine kinase is common in acute myelogenous leukemia. One such activating point mutation is the N822K replacement in the c-Kit protein. Here we investigate the selective cytotoxic ...