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Browsing by Author "Palotás A."

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Alzheimer's β-amyloid-induced depolarization of skeletal muscle fibers: Implications for motor dysfunctions in dementia

Mukhamedyarov M.; Grishin S.; Yusupova E.; Zefirov A.; Palotás A. (2009)

Numerous findings obtained over the last decades suggest that accumulation of β-amyloid peptide (βAP) plays the central role in the pathogenesis of Alzheimer's disease. It is well established that βAP has wide range of ...
Andes-virus-induced cytokine storm is partially suppressed by ribavirin

Khaiboullina S.; Rizvanov A.; Lombardi V.; Morzunov S.; Reis H.; Palotás A.; Jeor S. (2013)

Background: Microbe-induced over-activation of cytokines, especially tumour necrosis factor (TNF)-α, is key to the pathogenesis of hantavirus infection leading to severe inflammation with high mortality rate. Although ...
Bacterial enzymes effectively digest Alzheimer's β-amyloid peptide

Danilova Y.; Shagimardanova E.; Margulis A.; Toymentseva A.; Balaban N.; Rudakova N.; Rizvanov A.; Sharipova M.; Palotás A. (2014)

© 2014 Elsevier Inc. Aggregated β-amyloid peptides play key roles in the development of Alzheimer's disease, and recent evidence suggests that microbial particles, among others, can facilitate their polymerization. Bacterial ...
Biological insight, high-throughput datasets and the nature of neuro-degenerative disorders

Valente A.; Oliveira P.; Khaiboullina S.; Palotás A.; Rizvanov A. (2013)

Life sciences are experiencing a historical shift towards a quantitative, data-rich regime. This transition has been associated with the advent of bio-informatics: mathematicians, physicists, computer scientists and ...
Cannabidiol prevents lipopolysaccharide-induced sickness behavior and alters cytokine and neurotrophic factor levels in the brain

Tito P.A.L.; Bernardino T.C.d.S.; Bellozi P.M.Q.; da Silva M.C.M.; de Miranda A.S.; Vieira É.L.M.; Moreira F.A.; Palotás A.; de Oliveira A.C.P.; Reis H.J. (2021)

Background: Major depressive disorder (MDD) affects millions of people worldwide. While the exact pathogenesis is yet to be elucidated, the role of neuro-immune signaling has recently emerged. Despite major advances in ...
Characterization of the secretome of human tooth germ stem cells (hTGSCs) reveals neuro-protection by fine-tuning micro-environment

Yalvaç M.; Yarat A.; Mercan D.; Rizvanov A.; Palotás A.; Şahin F. (2013)

Bone-marrow-derived mesenchymal stem cells (MSCs) demonstrate neuro-protective effects in several disease models. By producing growth-factors, cytokines and chemokines, they promote survival of neurons in damaged brain ...
Cognitive Disposition to Wine Consumption: How the Brain Is Wired to Select the Perfect Bottle With a Novel Musical Twist

Soós G.; Csernák J.; Lakatos L.; Zsófi Z.; Palotás A. (2019)

© Copyright © 2019 Soós, Csernák, Lakatos, Zsófi and Palotás. Taste is not a veridical perception: it is modifiable by cognitive and affective processes, as well as by expectations. Even though molecular composition ...
Comparison and optimisation of transfection of human dental follicle cells, a novel source of stem cells, with different chemical methods and electro-poration

Yalvac M.; Ramazanoglu M.; Gumru O.; Sahin F.; Palotás A.; Rizvanov A. (2009)

Introduction Human dental follicle cells (HDFCs) derived from human impacted third molars (wisdom teeth) have been shown to be a significant source of adult stem cells. Generation of mesenchymal stem cell-like cells from ...
Construction of recombinant adenovirus containing picorna-viral 2A-peptide sequence for the co-expression of neuro-protective growth factors in human umbilical cord blood cells

Garanina E.; Mukhamedshina Y.; Salafutdinov I.; Kiyasov A.; Lima L.; Reis H.; Palotás A.; Islamov R.; Rizvanov A. (2015)

© 2015 International Spinal Cord Society Study design:Experimental study.Objective:Several neuro-degenerative disorders such as Alzheimer’s dementia, Parkinson’s disease and amyotrophic lateral sclerosis (ALS) are associated ...
Construction of recombinant adenovirus containing picorna-viral 2A-peptide sequence for the co-expression of neuro-protective growth factors in human umbilical cord blood cells

Garanina E.; Mukhamedshina Y.; Salafutdinov I.; Kiyasov A.; Lima L.; Reis H.; Palotás A.; Islamov R.; Rizvanov A. (2016)

© 2016 International Spinal Cord Society.Study design:Experimental study.Objective:Several neuro-degenerative disorders such as Alzheimer's dementia, Parkinson's disease and amyotrophic lateral sclerosis (ALS) are associated ...
Coronary artery bypass surgery provokes alzheimer's disease-like changes in the cerebrospinal fluid

Palotás A.; Reis H.; Bogáts G.; Babik B.; Racsmány M.; Engvau L.; Kecskeméti E.; Juhász A.; Vieira L.; Teixeira A.; Mukhamedyarov M.; Rizvanov A.; Yalvaç M.; Guimarêes M.; Ferreira C.; Zefirov A.; Kiyasov A.; Wang L.; Janka Z.; Kálmán J. (2010)

Several biomarkers are used in confirming the diagnosis of cognitive disorders. This study evaluates whether the level of these markers after heart surgery correlates with the development of cognitive dysfunction, which ...
Death-domain associated protein-6 (DAXX) mediated apoptosis in hantavirus infection is counter-balanced by activation of interferon-stimulated nuclear transcription factors

Khaiboullina S.; Morzunov S.; Boichuk S.; Palotás A.; Jeor S.; Lombardi V.; Rizvanov A. (2013)

Hantaviruses are negative strand RNA species that replicate predominantly in the cytoplasm. They also activate numerous cellular responses, but their involvement in nuclear processes is yet to be established. Using human ...
Different effects of ATP on the contractile activity of mice diaphragmatic and skeletal muscles

Grishin S.; Teplov A.; Galkin A.; Devyataev A.; Zefirov A.; Mukhamedyarov M.; Ziganshin A.; Burnstock G.; Palotás A. (2006)

Apart from acetyl-choline (Ach), adenosine-5′-trisphosphate (ATP) is thought to play a role in neuromuscular function, however little information is available on its cellular physiology. As such, effects of ATP and adenosine ...
Differential immuno-reactivity to genomic DNA, RNA and mitochondrial DNA is associated with auto-immunity

Ivanova V.; Khaiboullina S.; Cherenkova E.; Martynova E.; Nevzorova T.; Kunst M.; Sibgatullin T.; Maksudova A.; Oliveira P.; Lombardi V.; Palotás A.; Rizvanov A. (2014)

© 2015 S. Karger AG, Basel. Background: Circulating auto-reactive antibodies are hallmark features of auto-immune diseases, however little is known with respect to the specificity of such bio-markers. In the present study, ...
Differentiation and neuro-protective properties of immortalized human tooth germ stem cells

Yalvaç M.; Yilmaz A.; Mercan D.; Aydin S.; Dogan A.; Arslan A.; Demir Z.; Salafutdinov I.; Shafigullina A.; Sahin F.; Rizvanov A.; Palotás A. (2011)

Stem cells are considered to be promising therapeutic options in many neuro-degenerative diseases and injuries to the central nervous system, including brain ischemia and spinal cord trauma. Apart from the gold standard ...
Differentiation of human stem cells is promoted by amphiphilic pluronic block copolymers

Doǧan A.; Yalvaç M.; Şahin F.; Kabanov A.; Palotás A.; Rizvanov A. (2012)

Stem cell usage provides novel avenues of tissue regeneration and therapeutics across disciplines. Apart from ethical considerations, the selection and amplification of donor stem cells remain a challenge. Various biopolymers ...
Disease-specific expression of the serotonin-receptor 5-HT2C in natural killer cells in Alzheimer's dementia

Martins L.; Rocha N.; Torres K.; dos Santos R.; França G.; de Moraes E.; Mukhamedyarov M.; Zefirov A.; Rizvanov A.; Kiyasov A.; Vieira L.; Guimarães M.; Yalvaç M.; Teixeira A.; Bicalho M.; Janka Z.; Romano-Silva M.; Palotás A.; Reis H. (2012)

Alzheimer's dementia (AD) is a degenerative brain disorder characterized mainly by cholinergic failure, but other neuro-transmitters are also deficient especially at late stages of the disease. Misfolded β-amyloid peptide ...
Effects of Transplanted Umbilical Cord Blood Mononuclear Cells Overexpressing GDNF on Spatial Memory and Hippocampal Synaptic Proteins in a Mouse Model of Alzheimer's Disease

Petukhova E.; Mukhamedshina Y.; Salafutdinov I.; Garanina E.; Kaligin M.; Leushina A.; Rizvanov A.; Reis H.; Palotás A.; Zefirov A.; Mukhamedyarov M. (2019)

© 2019 - IOS Press and the authors. All rights reserved. Background/Objective: Alzheimer's disease (AD) is a progressive incurable neurodegenerative disorder. Glial cell line-derived neurotrophic factor (GDNF) is a prominent ...
Evaluating the effects of exercise on cognitive function in hypertensive and diabetic patients using the mental test and training system

Teixeira R.; Marins J.; Amorim P.; Teoldo I.; Cupeiro R.; Andrade M.; Martins Y.; Castilho P.; Magalhães D.; Palotás A.; Lima L. (2017)

© 2017 Informa UK Limited, trading as Taylor & Francis Group Objectives: Systemic arterial hypertension (SAH) and diabetes mellitus (DM) are important risk factors for developing cognitive impairment. General life-style ...
Evaluation of direct and cell-mediated triple-gene therapy in spinal cord injury in rats

Islamov R.; Izmailov A.; Sokolov M.; Fadeev P.; Bashirov F.; Eremeev A.; Shaymardanova G.; Shmarov M.; Naroditskiy B.; Chelyshev Y.; Lavrov I.; Palotás A. (2017)

© 2017 Elsevier Inc.Current treatment options for spinal cord injury (SCI) are scarce. One of the most promising innovative approaches include gene-therapy, however no single gene has so far been shown to be of clinical ...

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Browsing by Author "Palotás A."

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