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Browsing by Author "Khaiboullina S.F."

Now showing items 1-16 of 16

Cytokine, chemokine, and metalloprotease activation in the serum of patients with nephropathia epidemica from the republic of tatarstan and the republic of mordovia, Russia

Martynova E.; Davidyuk Y.; Kabwe E.; Garanina E.E.; Shakirova V.; Pavelkina V.; Uskova Y.; Stott R.J.; Foster T.L.; Markelova M.; Goyal M.; Gupta A.; Bhola M.; Kumar V.; Baranwal M.; Rizvanov A.A.; Khaiboullina S.F. (2021)

Nephropathia Epidemica (NE), endemic to several Volga regions of Russia, including the Republic of Tatarstan (RT) and the Republic of Mordovia (RM), is a mild form of hemorrhagic fever with renal syndrome caused by infection ...
Doxycycline attenuates cancer cell growth by suppressing nlrp3-mediated inflammation

Alsaadi M.; Tezcan G.; Garanina E.E.; Hamza S.; McIntyre A.; Rizvanov A.A.; Khaiboullina S.F. (2021)

NLR family pyrin domain containing 3 (NLRP3) inflammasome formation is triggered by the damaged mitochondria releasing reactive oxygen species. Doxycycline was shown to regulate inflammation; however, its effect on NLRP3 ...
Human mesenchymal stem cells overexpressing interleukin 2 can suppress proliferation of neuroblastoma cells in co-culture and activate mononuclear cells in vitro

Chulpanova D.S.; Solovyeva V.V.; James V.; Arkhipova S.S.; Gomzikova M.O.; Garanina E.E.; Akhmetzyanova E.R.; Tazetdinova L.G.; Khaiboullina S.F.; Rizvanov A.A. (2020)

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. High-dose recombinant interleukin 2 (IL2) therapy has been shown to be successful in renal cell carcinoma and metastatic melanoma. However, systemic administration ...
Immunological perspective for ebola virus infection and various treatment measures taken to fight the disease

Jain S.; Khaiboullina S.F.; Baranwal M. (2020)

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Ebolaviruses, discovered in 1976, belongs to the Filoviridae family, which also includes Marburg and Lloviu viruses. They are negative-stranded RNA viruses with six ...
Immunosuppressive properties of cytochalasin B-induced membrane vesicles of mesenchymal stem cells: comparing with extracellular vesicles derived from mesenchymal stem cells

Gomzikova M.O.; Aimaletdinov A.M.; Bondar O.V.; Starostina I.G.; Gorshkova N.V.; Neustroeva O.A.; Kletukhina S.K.; Kurbangaleeva S.V.; Vorobev V.V.; Garanina E.E.; Persson J.L.; Jeyapalan J.; Mongan N.P.; Khaiboullina S.F.; Rizvanov A.A. (2020)

© 2020, The Author(s). Extracellular vesicles derived from mesenchymal stem cells (MSCs) represent a novel approach for regenerative and immunosuppressive therapy. Recently, cytochalasin B-induced microvesicles (CIMVs) ...
Inflammasomes: Role in disease pathogenesis and therapeutic potential

Garanina E.E.; Martynova E.V.; Ivanov K.Y.; Rizvanov A.A.; Khaiboullina S.F. (2020)

© 2020 Kazan Federal University. All rights reserved. The structure of inflammasomes, history of their discovery, and their potential use as therapeutic targets were discussed. Inflammasomes represent cytosolic polyprotein ...
Long term immune response produced by the sputnikv vaccine

Martynova E.; Hamza S.; Garanina E.E.; Kabwe E.; Markelova M.; Shakirova V.; Khaertynova I.M.; Kaushal N.; Baranwal M.; Rizvanov A.A.; Urbanowicz R.A.; Khaiboullina S.F. (2021)

SputnikV is a vaccine against SARS-CoV-2 developed by the Gamaleya National Research Centre for Epidemiology and Microbiology. The vaccine has been shown to induce both humoral and cellular immune responses, yet the ...
Membrane microvesicles as potential vaccine candidates

Shkair L.; Garanina E.E.; Stott R.J.; Foster T.L.; Rizvanov A.A.; Khaiboullina S.F. (2021)

The prevention and control of infectious diseases is crucial to the maintenance and protection of social and public healthcare. The global impact of SARS-CoV-2 has demonstrated how outbreaks of emerging and re-emerging ...
Mesenchymal stem cell derived biocompatible membrane vesicles demonstrate immunomodulatory activity inhibiting activation and proliferation of human mononuclear cells

Gomzikova M.O.; Kletukhina S.K.; Kurbangaleeva S.V.; Neustroeva O.A.; Vasileva O.S.; Garanina E.E.; Khaiboullina S.F.; Rizvanov A.A. (2020)

© 2020, MDPI AG. All rights reserved. Immune-mediated diseases are characterized by abnormal activity of the immune system. The cytochalasin B-induced membrane vesicles (CIMVs) are innovative therapeutic instruments. ...
Mutational frequencies of SARS-CoV-2 genome during the beginning months of the outbreak in USA

Kaushal N.; Gupta Y.; Goyal M.; Khaiboullina S.F.; Baranwal M.; Verma S.C. (2020)

© 2020 by the authors. SARS-CoV-2 has spread very quickly from its first reported case on January 19th, 2020 in the United Stated of America, leading WHO to declare pandemic by March 11th, 2020. RNA viruses accumulate ...
Rab GTPase mediating regulation of NALP3 in colorectal cancer

Tezcan G.; Garanina E.E.; Zhuravleva M.N.; Hamza S.; Rizvanov A.A.; Khaiboullina S.F. (2020)

© 2020 by the authors. The NALP3 inflammasome signaling contributes to inflammation within tumor tissues. This inflammation may be promoted by the vesicle trafficking of inflammasome components and cytokines. Rab5, Rab7 ...
Recombinant histone H1.3 inhibits orthohantavirus infection in vitro

Chulpanova D.S.; Solovyeva V.V.; Isaeva G.S.; St. Jeor S.; Khaiboullina S.F.; Rizvanov A.A. (2020)

© 2020, Springer Science+Business Media, LLC, part of Springer Nature. Histones are proteins participating in DNA packaging. Despite this limited function, histones were shown to have antiviral activity. Histone H1.3 has ...
Serum and cerebrospinal fluid cytokine biomarkers for diagnosis of multiple sclerosis

Martynova E.; Goyal M.; Johri S.; Kumar V.; Khaibullin T.; Rizvanov A.A.; Verma S.; Khaiboullina S.F.; Baranwal M. (2020)

Copyright © 2020 Ekaterina Martynova et al. Background. Multiple sclerosis (MS) is a chronic debilitating disorder characterized by persisting damage to the brain caused by autoreactive leukocytes. Leukocyte activation is ...
The distribution of puumala orthohantavirus genome variants correlates with the regional landscapes in the trans-kama area of the republic of tatarstan

Davidyuk Y.N.; Kabwe E.; Shamsutdinov A.F.; Knyazeva A.V.; Martynova E.V.; Ismagilova R.K.; Trifonov V.A.; Savitskaya T.A.; Isaeva G.S.; Urbanowicz R.A.; Khaiboullina S.F.; Rizvanov A.A.; Morzunov S.P. (2021)

In the European part of Russia, the highest number of hemorrhagic fever with renal syndrome (HFRS) cases are registered in the Volga Federal District (VFD), which includes the Republic of Tatarstan (RT). Puumala orthohantavirus ...
The relationship of the mechanisms of the pathogenesis of multiple sclerosis and the expression of endogenous retroviruses

Lezhnyova V.R.; Martynova E.V.; Khaiboullin T.I.; Urbanowicz R.A.; Khaiboullina S.F.; Rizvanov A.A. (2020)

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Two human endogenous retroviruses of the HERV‐W family can act as cofactors triggering multiple sclerosis (MS): MS‐associated retrovirus (MSRV) and ERVWE1. Endogenous ...
Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer

Tezcan G.; Garanina E.E.; Alsaadi M.; Gilazieva Z.E.; Martinova E.V.; Markelova M.I.; Arkhipova S.S.; Hamza S.; McIntyre A.; Rizvanov A.A.; Khaiboullina S.F. (2021)

Introduction: Dysregulation of NLRP3 inflammasome complex formation can promote chronic inflammation by increased release of IL-1β. However, the effect of NLRP3 complex formation on tumor progression remains controversial. ...

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Browsing by Author "Khaiboullina S.F."

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