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Browsing by Author "Chao C."

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A comprehensive analysis of fibroblast growth factor receptor 2b signaling on epithelial tip progenitor cells during early mouse lung branching morphogenesis

Jones M.; Dilai S.; Lingampally A.; Chao C.; Danopoulos S.; Carraro G.; Mukhametshina R.; Wilhelm J.; Baumgart-Vogt E.; Al Alam D.; Chen C.; Minoo P.; Zhang J.; Bellusci S. (2019)

© 2007 - 2019 Frontiers Media S.A. All Rights Reserved. This study demonstrates that FGF10/FGFR2b signaling on distal epithelial progenitor cells, via ß-catenin/EP300, controls, through a comprehensive set of developmental ...
A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development

Shrestha A.; Carraro G.; Nottet N.; Vazquez-Armendariz A.; Herold S.; Cordero J.; Singh I.; Wilhelm J.; Barreto G.; Morty R.; El Agha E.; Mari B.; Chen C.; Zhang J.; Chao C.; Bellusci S. (2019)

© 2019, Springer Nature Switzerland AG. The respiratory epithelium arises from alveolar epithelial progenitors which differentiate into alveolar epithelial type 1 (AT1) and type 2 (AT2) cells. AT2 cells are stem cells in ...
Evidence for the involvement of fibroblast growth factor 10 in lipofibroblast formation during embryonic lung development

Al Alam D.; El Agha E.; Sakurai R.; Kheirollahi V.; Moiseenko A.; Danopoulos S.; Shrestha A.; Schmoldt C.; Quantius J.; Herold S.; Chao C.; Tiozzo C.; De Langhe S.; Plikus M.; Thornton M.; Grubbs B.; Minoo P.; Rehan V.; Bellusci S. (2015)

© 2015. Published by The Company of Biologists Ltd. Lipid-containing alveolar interstitial fibroblasts (lipofibroblasts) are increasingly recognized as an important component of the epithelial stem cell niche in the rodent ...
FGF10 promotes regional foetal cardiomyocyte proliferation and adult cardiomyocyte cell-cycle re-entry

Rochais F.; Sturny R.; Chao C.; Mesbah K.; Bennett M.; Mohun T.; Bellusci S.; Kelly R. (2014)

© The Author 2014. Aims Cardiomyocyte proliferation gradually declines during embryogenesis resulting in severely limited regenerative capacities in the adult heart. Understanding the developmental processes controlling ...
Generation and validation of MIR-142 knock out mice

Shrestha A.; Carraro G.; El Agha E.; Mukhametshina R.; Chao C.; Rizvanov A.; Barreto G.; Bellusci S.; Kalinichenko V. (2015)

© 2015 Shrestha et al.This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
Impact of Fgf10 deficiency on pulmonary vasculature formation in a mouse model of bronchopulmonary dysplasia

Chao C.; Moiseenko A.; Kosanovic D.; Rivetti S.; El Agha E.; Wilhelm J.; Kampschulte M.; Yahya F.; Ehrhardt H.; Zimmer K.; Barreto G.; Rizvanov A.; Schermuly R.; Reiss I.; Morty R.; Rottier R.; Bellusci S.; Zhang J. (2019)

© 2018 The Author(s) 2018. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com. Bronchopulmonary dysplasia (BPD), characterized by alveoli simplification ...
Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis

Rubio K.; Singh I.; Dobersch S.; Sarvari P.; Günther S.; Cordero J.; Mehta A.; Wujak L.; Cabrera-Fuentes H.; Chao C.; Braubach P.; Bellusci S.; Seeger W.; Günther A.; Preissner K.; Wygrecka M.; Savai R.; Papy-Garcia D.; Dobreva G.; Heikenwalder M.; Savai-Pullamsetti S.; Braun T.; Barreto G. (2019)

© 2019, The Author(s). Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and highly lethal lung disease with unknown etiology and poor prognosis. IPF patients die within 2 years after diagnosis mostly due to ...
Non-invasive lung cancer diagnosis by detection of GATA6 and NKX2-1 isoforms in exhaled breath condensate

Mehta A.; Cordero J.; Dobersch S.; Romero-Olmedo A.; Savai R.; Bodner J.; Chao C.; Fink L.; Guzmán-Díaz E.; Singh I.; Dobreva G.; Rapp U.; Günther S.; Ilinskaya O.; Bellusci S.; Dammann R.; Braun T.; Seeger W.; Gattenlöhner S.; Tresch A.; Günther A.; Barreto G. (2016)

© 2016 The Authors. Published under the terms of the CC BY 4.0 licenseLung cancer (LC) is the leading cause of cancer-related deaths worldwide. Early LC diagnosis is crucial to reduce the high case fatality rate of this ...
Origin and characterization of alpha smooth muscle actin-positive cells during murine lung development

Moiseenko A.; Kheirollahi V.; Chao C.; Ahmadvand N.; Quantius J.; Wilhelm J.; Herold S.; Ahlbrecht K.; Morty R.; Rizvanov A.; Minoo P.; El Agha E.; Bellusci S. (2017)

© 2017 The Authors Stem Cells published by Wiley Periodicals, Inc. on behalf of AlphaMed PressACTA2 expression identifies pulmonary airway and vascular smooth muscle cells (SMCs) as well as alveolar myofibroblasts (MYF). ...
Translational research in acute lung injury and pulmonary fibrosis attenuating endogenous Fgfr2b ligands during bleomycin-induced lung fibrosis does not compromise murine lung repair

Mackenzie B.; Henneke I.; Hezel S.; Alam D.; Agha E.; Chao C.; Quantius J.; Wilhelm J.; Jones M.; Goth K.; Li X.; Seeger W.; Königshoff M.; Herold S.; Rizvanov A.; Günther A.; Bellusci S. (2015)

© 2015 the American Physiological Society Fibroblast growth factors (Fgfs) mediate organ repair. Lung epithelial cell overexpression of Fgf10 postbleomycin injury is both protective and therapeutic, characterized by increased ...

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Browsing by Author "Chao C."

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